Can health information exchanges (HIEs) survive the present moment? The question might seem overly simplistic, but the reality, as knowledgeable observers note, is that broad-based, and particularly statewide, HIEs are indeed failing or faltering across the country. Indeed, many public and semi-public statewide HIEs are struggling these days, in the wake of the dwindling of federal and state grants to support them. What are industry observers seeing?