What happens when you bring together several key ingredients—an organization-wide push for clinical performance improvement; a multidisciplinary approach to such improvement, with buy-in from clinician, administrative and IT stakeholder groups; and the discipline to apply analytics to complex care delivery processes, in pioneering ways? Well, if you are the leaders at Texas Children’s Hospital, and you have the strategic vision, the intelligence, and the perseverance to see things through, you get industry-leading change.