Will health information exchanges, as a class, survive the present moment of instability? Will the ongoing advances in wearable device technology lead to a blooming of patient-generated data for care management? Will patient care organizations develop comprehensively successful strategies that make doctors truly mobile in their day-to-day practices? Will hospitals, large medical groups, and integrated health systems be able to find and cultivate the clinical informaticists leaders they need in order to move to the next level of clinical transformation?